Spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester of pregnancy
Received 14 February 2007; received in revised form 29 November 2008; accepted 1 December 2008. published online 23 October 2009.
Abstract
Study Objective
To compare the spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester pregnant and non-pregnant women.
Design
Prospective study.
Setting
University teaching hospital.
Patients
44 ASA physical status I and II women patients, 22 of whom were in their second trimester of pregnancy undergoing cervical cerclage, and 22 non-pregnant women scheduled for perianal surgery.
Interventions
The extent of sensory block and hemodynamic changes were assessed.
Measurements
Number of dermatomes blocked was determined by testing for pinprick; systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured at 3, 5, 10, 15, 30 and 60 minutes.
Main Results
Maximal sensory block was higher in the second trimester of the pregnant group by three dermatomes than the non-pregnant group. There were no statistically significant differences in SBP, DBP, or HR changes between the groups.
Conclusion
Pregnant women in the second trimester exhibit enhanced spread of spinal analgesia with hyperbaric bupivacaine more so than non-pregnant women.
ABSTRACT