Journal of Clinical Anesthesia
Volume 22, Issue 5 , Pages 313-317 , August 2010

Liposomal encapsulation improves the duration of soft tissue anesthesia but does not induce pulpal anesthesia

  • Michelle Franz-Montan, MSc (Doctoral Student)

      Affiliations

    • Department of Physiological Sciences, Piracicaba Dentistry School, State University of Campinas – UNICAMP, 13414-903 Piracicaba, São Paulo, Brazil
  • ,
  • André L.R. Silva, MSc (Doctoral Student)

      Affiliations

    • Department of Biochemistry, Institute of Biology, State University of Campinas – UNICAMP, 13083-862 Campinas, São Paulo, Brazil
  • ,
  • Leonardo F. Fraceto, PhD (Associate Professor)

      Affiliations

    • Department of Environmental Engineering, Julio de Mesquita Filho State University, 18087-180 Sorocaba, São Paulo, Brazil
  • ,
  • Maria C. Volpato, PhD (Professor)

      Affiliations

    • Department of Physiological Sciences, Piracicaba Dentistry School, State University of Campinas – UNICAMP, 13414-903 Piracicaba, São Paulo, Brazil
  • ,
  • Eneida de Paula, PhD (Associate Professor)

      Affiliations

    • Department of Biochemistry, Institute of Biology, State University of Campinas – UNICAMP, 13083-862 Campinas, São Paulo, Brazil
  • ,
  • José Ranali, PhD (Professor)

      Affiliations

    • Department of Physiological Sciences, Piracicaba Dentistry School, State University of Campinas – UNICAMP, 13414-903 Piracicaba, São Paulo, Brazil
  • ,
  • Francisco C. Groppo, PhD (Professor)

      Affiliations

    • Department of Physiological Sciences, Piracicaba Dentistry School, State University of Campinas – UNICAMP, 13414-903 Piracicaba, São Paulo, Brazil
    • Corresponding Author InformationCorresponding author. CEP: 13414-903 Piracicaba, São Paulo, Brazil. Tel.: +55 19 2106 5310; fax: +55 19 2106 5218.

Received 1 May 2008 ,Revised 11 August 2009 ,Accepted 22 March 2010.

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 Supported by DFL Ind Com Ltda, Rio de Janeiro, Brazil, who supplied the the 20% benzocaine used in this study; and by a grant to Michelle Franz-Montan, MS, from the Conselho Nacional de Pesquisa – CNPq, Brasilia City, Brazil.

PII: S0952-8180(10)00100-5

doi: 10.1016/j.jclinane.2010.03.001

Journal of Clinical Anesthesia
Volume 22, Issue 5 , Pages 313-317 , August 2010