Journal of Clinical Anesthesia
Volume 22, Issue 5 , Pages 363-366, August 2010

Femoral and sciatic nerve block with 0.25% bupivacaine for surgical management of diabetic foot syndrome: an anesthetic technique for high-risk patients with diabetic nephropathy

  • Aysu Kocum, MD (Staff Anesthesiologist)

      Affiliations

    • Corresponding Author InformationCorresponding author. Baskent University, Faculty of Medicine, Adana Teaching and Medical Research Center, 01110, Seyhan/Adana, Turkey. Tel.: +90 322 458 6868 1226; fax: +90 322 459-2622.
  • ,
  • Ayda Turkoz, MD (Associate Professor)
  • ,
  • Nesrin Bozdogan, MD (Staff Anesthesiologist)
  • ,
  • Esra Caliskan, MD (Assistant Professor)
  • ,
  • Evren H. Eker, MD (Staff Anesthesiologist)
  • ,
  • Gulnaz Arslan, MD (Professor)

Department of Anesthesiology and Reanimation, Baskent University Faculty of Medicine, Ankara 06530, Turkey

Received 23 September 2008; received in revised form 20 April 2009; accepted 28 April 2009.

Abstract 

A case series of patients with diabetic nephropathy, who underwent lower limb debridement or amputation below the knee during successful combined sciatic and femoral nerve block with bupivacaine 0.25%, is presented. Because impaired nerve conduction in diabetes mellitus results in lower local anesthetic agent requirement, a dose-sparing, minimal effective concentration for surgical anesthesia for peripheral nerve blockade may be more favorable for patients with diabetes and chronic renal disease.

Keywords: Bupivacaine, Diabetic foot, Diabetic nephropathy, Femoral nerve block, sciatic nerve block

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PII: S0952-8180(10)00132-7

doi:10.1016/j.jclinane.2009.04.009

Journal of Clinical Anesthesia
Volume 22, Issue 5 , Pages 363-366, August 2010