Journal of Clinical Anesthesia
Volume 24, Issue 1 , Pages 3-7 , February 2012

Meta-analysis of the effect of central neuraxial regional anesthesia compared with general anesthesia on postoperative natural killer T lymphocyte function

  • Ian Conrick-Martin, FCAI, MRCPI, DIBICM (Specialist Registrar in Anaesthesia)

      Affiliations

    • Department of Anaesthesia, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland
    • Corresponding Author InformationCorrespondence: Ian Conrick-Martin, FCAI, MRCPI, DIBICM, Department of Anaesthesia, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland. Tel.: +353 1 803-2281; fax: +353 1 830-9563.
  • ,
  • Malcolm R. Kell, MD, FRCSI, FRCS(Glasg) (Consultant Surgeon)

      Affiliations

    • Department of Surgery, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland
  • ,
  • Donal J. Buggy, MD, MSc, FRCPI, FCAI, FRCA (Professor of Anaesthesia; Consultant in Anaesthesia)

      Affiliations

    • Department of Anaesthesia, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland
    • Outcomes Research Consortium, Cleveland Clinic, OH, USA

Received 4 September 2010 ,Revised 3 August 2011 ,Accepted 6 September 2011.

  • Image Result

    Trial flow chart.

    Trial flow chart.

  • Image Result

    Fixed-effects and random-effects odds ratio meta-analysis plots. The overall fixed-effect odds ratio (OR) was 0.86 (95% CI = 0.66-1.14, P = 0.25) and the random-effect OR was 1.13 (95% CI = 0.26 - 4.9

    Fixed-effects and random-effects odds ratio meta-analysis plots. The overall fixed-effect odds ratio (OR) was 0.86 (95% CI = 0.66-1.14, P = 0.25) and the random-effect OR was 1.13 (95% CI = 0.26 - 4.92, P = 0.79).

 Supported by the Sisk Foundation, Dublin, and the Eccles Breast Cancer Research Fund, Dublin, Ireland.

PII: S0952-8180(11)00326-6

doi: 10.1016/j.jclinane.2011.09.001

Journal of Clinical Anesthesia
Volume 24, Issue 1 , Pages 3-7 , February 2012